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Sandra
L. McLellan
Assistant
Scientist
Great Lakes WATER Institute, UWM
Phone: (414)
382-1710
Fax: (414)
382-1705
E-Mail:
Web
Site: WATER
Profile page
Great
Lakes WATER Institute
600 E. Greenfield Ave.
Milwaukee, WI 53204 |
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Research Interests
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The
major research focus of my laboratory is to investigate the connections
between environmental processes and human health. Waterborne disease
is a leading cause of morbidity and mortality worldwide. There is
little understanding of the population genetics and ecology of these
organisms as they move through environmental reservoirs, particularly
in freshwater and marine systems. Large freshwater systems, such
as the Great Lakes, can act as a both a sink and reservoir. Understanding
the parameters that either drive or limit the disease cycle in these
systems is critical to delineating the processes that link infected
individuals to new hosts through contaminated surface waters.
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Education
| • | Ph.D., University of Cincinnati,
1998 |
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| • | B.S., University of Wisconsin-Milwaukee,
1990 |
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Selected Publications
| • | McLellan, SL. Genetic
diversity of Escherichia coli isolated from urban rivers and beach
water. Appl Environ Microbiol. 2004 Aug;70(8):4658-65. |
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| • | Salmore, AK, ET Jensen,
SL McLellan. Delineation of a chemical and biological signature for stormwater
pollution in urban rivers. (submitted for publication) |
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| • | Kinzelman, J, SL McLellan,
AD Daniels, S Cashin, A Singh, S Gradus, R Bagley. Non-point source pollution:
Determination of replication versus persistence of
Escherichia coli in surface water and sand and correlation of levels
with readily measurable environmental parameters. Journal of Water & Health 2004
Jun;2(2):103-14. |
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| • | McLellan, SL, AD Daniels,
AK Salmore. 2003. Genetic characterization of
Escherichia coli populations from host sources of fecal pollution
using DNA fingerprinting. Appl. Environ. Microbiol. 69:2587-94.  |
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| • | McLellan SL and AK Salmore.
2003. Evidence for localized bacterial loading as the cause of chronic
beach closings in a freshwater marina. Water Research 37:2700-8. |
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| • | McLellan SL, AD Daniels,
AK Salmore. 2001. Clonal populations of thermotolerant Enterobacteriaceae
in recreational water and their potential interference with fecal Escherichia
coli counts. Appl. Environ. Microbiol. 67:4934-8. |
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| • | McLellan SL, J Shann,
D Warshawsky. 2002. Inhibition and enhancement by low molecular weight
polycyclic aromatic hydrocarbons on the metabolism of benzo[a]pyrene in Mycobacterium sp.
RJGII-135. Environ. Tox. Chem. 21:253-59. |
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