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Peggy R. Biga
Assistant Scientist
Phone: (414) 382-1764
Fax: (414) 382-1705
E-Mail:
Great Lakes WATER Institute
600 E. Greenfield Ave.
Milwaukee, WI 53204 |
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Research Interests
The specific focuses of my research include:
- The molecular and hormonal regulation of muscle growth and development, with primary interest in muscle disease and metabolic dysfunction
- The development and validation of a comparative muscle growth model system
utilizing zebrafish and the giant danio
- The genetic contribution to susceptibility to diet-induced metabolic dysfunction (diabesity)
- The effects of environmental factors on energy balance, feeding behavior, and
metabolic disease
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Education
- B.S. Animal Science, Angelo State University (San Angelo, TX), 1997
- M.S. Ruminant Nutrition, Angelo State University (San Angelo, TX), 1999
- Ph.D. - University of Idaho (Moscow, ID), 2003
Dissertation title: "Effects of recombinant bovine somatotropin on
growth-related genes in rainbow trout (Oncorhynchus mykiss)."
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Publications
- Biga,
P.R. and F.W. Goetz. 2006. Zebrafish and giant danio as models
for muscle growth: Determinate versus indeterminate growth as
determined by morphometric analysis. Am J Physiol: Reg. Integ. Comp.
Physiol. 291:R1327-R1337.
- Biga, P.R., Roberts S.R., Iliev D.B., McCauley L.A.R., Moon JS, Collodi P, and Goetz F.W. 2005. The isolation, characterization, and expression of a novel GDF11 gene and a second myostatin form in zebrafish, Danio rerio. Comp Biochem Phys. B. 141:218-230.
- Biga, P.R., B.C. Peterson, G.T. Schelling, R.W. Hardy, K.D. Cain, K. Overturf,
and T.L. Ott. 2004 Serum somatotropin, insulin-like growth factor-I, and antibody
production in rainbow trout (Oncorhynchus mykiss) treated with sustained-
release bovine somatotropin (rbST). Accepted Aquaculture.
- Ettensohn K.M., Biga P., Romano C., Devlin R.H., Roberts S.B. 2004. Genes differentially expressed in growth hormone transgenic salmon. Biol Bull. Oct;207(2):168.
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Biga, P.R., K.D. Cain, R.W. Hardy, G.T. Schelling, K. Overturf, S.B. Roberts, F.W. Goetz, and T.L. Ott. 2004 Growth hormone differentially regulates myostatin-I and –II and increases circulating cortisol in rainbow trout (Oncorhynchus mykiss). Gen. Comp. Endocrinol. 138(1):32-41.
- Congleton, J.L., P.R. Biga, and B.C. Peterson. 2004. Plasma insulin-like growth factor-I in yearling Chinook salmon (Oncorhynchus tshawytscha) migrating from the Snake River Basin, USA. Fish Physiol. Biochem. 29:57-66.
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Biga, P.R., K.D. Cain, R.W. Hardy, K. Overturf, G.T. Schelling, and T.L. Ott. 2004 The effects of recombinant bovine somatotropin (rbST) on tissue IGF-I, IGF-I receptor, and GH mRNA levels in rainbow trout (Oncorhynchus mykiss). Gen. Comp. Endocrinol. 135(3):324-333.
[PubMed]
- Peterson, B.C., P.R. Simpson, K.D. Cain, R.W. Hardy, G.T. Schelling, and T.L. Ott. 2003. Immunoneutralization of SS in rainbow trout administration of somatostatin-14 and immunoneutralization of somatostatin in rainbow trout (Oncorhynchus mykiss). J. Fish. Biol. 63:506-522.
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